Host Antigen as the Sulphated Moiety of Influenza Virus Haemagglutinin
نویسندگان
چکیده
منابع مشابه
Bacillus subtilis as a Host for Recombinant Hemagglutinin Production of the Influenza A (H5N1) Virus
Abstract Background and Aims: Influenza A(H5N1) viruses circulating in animals might evolve and acquire the ability to spread from human to human and thus start a pandemic. Hemagglutinin (HA) has been shown to play a major role in binding of influenza virus to its target cell and the main neutralizing antibody responses elicit against this region. Recent studies have shown that...
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Background: A new pandemic influenza A (H1N1) emerged in April 2009, causing considerable morbidity and mortality. Since mutations in the haemagglutinin (HA) may influence the antigenicity and pathogenicity of the virus, continued epidemiological and molecular characterization for the effective control of pandemic flu and developing of more appropriate vaccine is crucial. Objective: To monitor ...
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The impending influenza virus pandemic requires global vaccination to prevent large-scale mortality and morbidity, but traditional influenza virus vaccine production is too slow for rapid responses. In this study, bacterial system has been developed for expression and purification of properly folded HA1 antigen as a rapid response to emerging pandemic strains. Here, a recombinant H5N1 (A/Indone...
متن کاملbacillus subtilis as a host for recombinant hemagglutinin production of the influenza a (h5n1) virus
abstract background and aims: influenza a(h5n1) viruses circulating in animals might evolve and acquire the ability to spread from human to human and thus start a pandemic. hemagglutinin (ha) has been shown to play a major role in binding of influenza virus to its target cell and the main neutralizing antibody responses elicit against this region. recent studies have shown that glycosylation ...
متن کاملbacillus subtilis as a host for recombinant hemagglutinin production of the influenza a(h5n1) virus
background and aims: influenza a(h5n1) viruses circulating in animals might evolve and acquire the ability to spread from human to human and thus start a pandemic. hemagglutinin (ha) has been shown to play a major role in binding of influenza virus to its target cell and the main neutralizing antibody responses elicit against this region. recent studies have shown that glycosylation of ha is ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1978
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-41-2-283